Plant Viruses as Adjuvants for Next-Generation Vaccines and Immunotherapy

Vaccines are the cornerstone of infectious disease control and prevention. The outbreak SARS-CoV-2 has confirmed urgent need for a new approach to design novel vaccines. Plant viruses their derivatives being used increasingly development medical biotechnological applications, this is reflected in number preclinical clinical studies. have unique combination features (biosafety, low reactogenicity, inexpensiveness ease production, etc.), which determine potential. This review presents latest data on use plant with different types symmetry as vaccine components adjuvants cancer immunotherapy. discussion concludes that most promising approaches might be those structurally modified (spherical particles) obtained from Tobacco mosaic virus. These particles combine high adsorption properties (as carrier) strong immunogenicity, been using various antigens animal models. According current research, it evident great potential application vaccines